LPGZL Large-scale Industrial Vacuum Lyophilizer Freeze Dryer is made by our company which is designed and manufactured strictly according to GMP specifications, and has the following advantages:
1. All the parts contacting the products are made of AISL 316L stainless steel, the surface roughness reaches R α≤0.5μm.
2. The inner circle of the chest has a smooth transition without dead corner, no objects accumulated.
3. Consider for user, the structure is easy to clean.
4. Option for steam sterilization or chemical sterilization.
Except for the above, our company can also provide automatic running CIP (cleaning in place) and SIP (sterilize in place) functions to ensure the high quality of cleaning and the sterilization of the equipment.
SIP:
1. Use overheats pure steam (121oC).
2. Equipped with cooling water jacket, after sterilizing, it can fast reduce the temperature of the chest (if less than 20m2, the equipment is optional, if larger than 20m2, the equipment is standard configuration.)
3. Optional pneumatic door lock, it locks automatically.
4. Use import sterilization filter to ensure the absolutely sterilized air coming into equipment.
5. The chest and various kinds of container and tube are all wrapped with import insulating layer to efficiently avoid from heat transmission.
6. Can carry out constant humidity control to the refrigeration humidity.
7. Equipped with water circulation pump capable to eliminate residual water in sterilization layer.
CIP:
1. The high-pressure water thoroughly wash inner surface of the chest and condenser.
2. Equipped with large flow rate CIP pump.
3. Fixed with CIP tubing that automatically drains the residual water.
4. Use rotary and fixed nozzle with 360-degree spray.
5. The hydraulic system uses isolated retractable corrugated tube.
The vacuum system has the following characteristics:
1. Standard configuration, uses double stage oil sealing revolving plate pump.
2. Option: ULVAC or Edwards pump.
3. Equipped with two vacuum probes, for measuring the vacuum level of freeze drying chest and pump respectively.
4. Option: condenser type vacuum meter.
5. There are two methods for drying chamber vacuum level control:
5-1. Drying chamber vacuum level controls the opening and closing of the air inlet valve, introduces the sterilized air from sterilized room.
5-2. Drying chamber vacuum level controls the opening degree of the big butterfly valve to reach the purpose of controlling the vacuum level.
Control and optimum disposition:
The control system of the freeze drier provides a reliable whole procedure control for the freeze drier. It has advanced functions of display, control, recording, printing and alarming. The control system has the following characteristics:
1. The main air switch, transformer and AC contactor fixed in electric cabinet are Siemens products. The electric cabinet is secured on machine frame. All machine pump motors are equipped with overheat protection, solenoid valve and heating circuit are equipped with separate protection.
2. The display screen uses touch screen, PLC programmable logic controller, indicating light, sound-light alarming system and etc.
3. Temperature measuring, pressure measuring, the components can work normally under high temperature, ultra-low temperature and high vacuum level with high reliability.
4. The control system can display the running status of all components of the whole system, and can store and process the operation information and various data. It can provide procedure recording report of whole freeze-drying process. It can set freeze-drying curve, monitor each status in freeze-drying procedure. It can alarm on failure or abnormal situation, provide checking for maintenance, the operator can set and modify data and steps.
Technical Parameter
Model | LPGZL1 | LPGZL2 | LPGZL3 | LPGZL5 | LPGZL6 | LPGZL8 | LPGZL10 |
Shelf area (m2) | 1 | 2 | 3 | 5 | 6 | 8 | 10 |
Shelf size (mm) | 405X610 | 610X810 | 810X915 | 915X1220 | 915X1215 | 915X1220 | 1215X1220 |
Number of shelf | 4+1 | 4+1 | 4+1 | 5+1 | 5+1 | 7+1 | 7+1 |
Shelf spacing (mm) | 100 | 100 | 100 | 100 | 100 | 100 | 100 |
Shelf smoothness (mm/m) | ±0.5 | ±0.5 | ±0.5 | ±0.5 | ±0.5 | ±0.5 | ±0.5 |
Shelf surface roughness (Ra) | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 |
Shelf temperature scope(°C) | -55~+80 | -55~+80 | -55~+80 | -55~+80 | -55~+80 | -55~+80 | -55~+80 |
Shape of chest | rectangular | rectangular | rectangular | rectangular | rectangular | rectangular | rectangular |
Chest inner surface polish | mirror | mirror | mirror | mirror | mirror | mirror | mirror |
Structure and shape of water capturer | horizontal cylinder | horizontal cylinder | horizontal cylinder | horizontal cylinder | horizontal cylinder | horizontal cylinder | horizontal cylinder |
Lowest temperature of water condenser (°C) | -75 | -75 | -75 | -75 | -75 | -75 | -75 |
Capturing amount of water condenser (kg) | 20 | 40 | 60 | 75 | 100 | 120 | 200 |
Control system | automatic+manual | automatic+manual | automatic+manual | automatic+manual | automatic+manual | automatic+manual | automatic+manual |
Power of whole machine (Kw) | 30 | 35 | 40 | 75 | 75 | 75 | 75 |
Cooling water amount (m3/h) | 5 | 5 | 5 | 12 | 12 | 12 | 12 |
SIP (option) | √ | √ | √ | √ | √ | √ | √ |
CIP (option) | √ | √ | √ | √ | √ | √ | √ |
Freeze-drying plate (option) | √ | √ | √ | √ | √ | √ | √ |
Diagram recording instrument | √ | √ | √ | √ | √ | √ | √ |
Weight of whole machine (kg) | 3500 | 4000 | 4500 | 5500 | 5500 | 8500 | 8500 |
Vials quantity for Φ 22mm | 2100pcs | 4200pcs | 6200pcs | 10300pcs | 11300pcs | 16500pcs | 21300pcs |
Pictures